Function of the Blood-Brain Barrier and Restriction of Drug Delivery to Invasive Glioma Cells: Findings in a Orthotopic Rat Xenograft Model of Glioma

Department of Pharmaceutics, Brain Barriers Research Center, University of Minnesota, 9-177 Weaver Densford Hall, 308 Harvard Street SE, Minneapolis, MN, 55455, USA (S.A., J.R.O., W.F.E.) Brain Tumor and Neuro-Oncology Center, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH, 44195, USA (P.M., M.A.V.) Department of Pediatrics, University of Minnesota, 2-197J Moos Tower, 515 Delaware St. SE, Minneapolis, MN, 55455, USA. (J.R.O.) DMD Fast Forward. Published on September 26, 2012 as doi:10.1124/dmd.112.048322